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WSLH Proficiency Testing

Wisconsin State Laboratory of Hygiene

Author: flowerme

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A Conversation with Dr. Kurtycz

Recently, our outreach coordinator, Megan Flowers had an opportunity to sit down with Dr. Dan Kurtycz, who has served as medical director for the Wisconsin State Lab of Hygiene (WSLH) since 1998. Dr. Kurtycz or, “DK” as his students call him, will be retiring at the end of this year. Before he sets sail for his retirement years, we wanted to gather his reflections on his time in the medical community and in the world of proficiency testing through his eyes as medical director for WSLH, the public health lab which is the home of WSLH Proficiency Testing. Below you’ll find an excerpt of the interview Megan had with DK and some of the fascinating conversations shared.

Megan Flowers: How have you seen the world of proficiency testing change since you began your career?

Dan Kurtycz: It’s really come a long way since I started out as a junior pathologist. There were about a dozen proficiency testing providers during the time of my residency where they would start sending samples out of known concentrations and got to see if laboratories would get the same answers. People began complaining, well, you weren’t testing properly and my method is better; so, you began to start seeing controversies.
When I finished residency, there was a program run by the College of American Pathologists called QAS today, where you would send samples out to people and you would test them and give them an answer in their peer group. I was involved in this program as a junior pathologist, and had signed up with CAP to help them. We were in charge of a region where we reviewed everyone’s numbers and notified them when they failed or when they were too far out.

What constitutes being too far out? Dr. Jim Westgard was really important in all of this.  I actually did a fellowship with Dr. Westgard around 1983. Dr. Westgard had involved these things called control rules. If you are running a series of controls with relatively good tolerance limits there is a bell-shaped curve of results that people are going to get. Within this bell-shaped curve, you want everyone to be within at least your results within at least 95% acceptance limits, which by the way is a much higher success rate than what clinicians do when they are diagnosing patients. Westgard evolved a series of rules based in part on 95% confidence limits, 2 standard deviations out from a mean. Westgard’s control rules became very important in the literature and then became built into the machines.  For example, if you have one error in which everything is on one side of the mean then that is likely a systemic error and something is likely wrong with your machine’s calibration or the reagents you are using. Westgard’s series of rules became very important and was promulgated across the nation and around the world from right here in Wisconsin. Everyone was building his methods into their day-to-day practice. I really learned a lot from Dr. Westgard and the whole bevy of people who got involved in Westgard rules and helping refine them.

MF: In the case of the Wisconsin State Lab of Hygiene, what is the significance of having a public health lab also operate as a proficiency testing provider, that entity being  WSLH Proficiency Testing?

DK: Having a division of our lab focused on providing proficiency testing programs was from my predecessor’s efforts, Dr. Ronald Laessig, who was the Medical Director of WSLH at the time. It was important for WSLH as a national public health lab to outreach and provide support to clinical labs on all fronts, including helping labs improve their patient testing through proficiency testing. This was at the same time Laessig was working with Westgard to expand improved methodology and machines. Historically I’ve been more involved with CAP, since I work with CAP as the Medical Director of WSLH. However, what makes WSLH Proficiency Testing stand out in the world of proficiency testing is the ability to provide personable, one-on-one consultations when the laboratory professional needs it. That means a lot.

MF: What advice would you give clinical laboratories regarding their approach to proficiency testing today?

DK: Well, it’s not only about getting the numbers right. It has to be a part of a whole quality assurance program. They have to pay attention to everything from the pre-analytics through the actual testing, running the controls, and to the post-analytics. Quality isn’t only just about making sure your controls are in nowadays. The biggest errors in the laboratory are clerical, where we mess up, don’t track the specimens, and don’t get the right answers to the right people. Also, as laboratory professionals, we need to make it as easy as possible for the clinician to get what they need to take care of people. We tend to run our laboratories as factories and we forget sometimes about the patient at the end of every sample, including those proficiency testing samples that, in the end, help us better alleviate a patient’s suffering. We are not isolated in this work. We are part of the medical community. Let’s not forget the important work we do.

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WSLH PT Blog

Bringing you clinical lab features, news, and updates via the WSLH PT Blog! If you are interested in receiving an email digest of news along with curated staff picks from around the internet, sign up for WSLH PT’s monthly newsletter, The MedLab Retriever.

Public Health: A Heroic History

L0025222 Plague doctor
Credit: Wellcome Library, London. Wellcome Images
images@wellcome.ac.uk
http://wellcomeimages.org
Plague doctor: ein Kleydung under den Todt.
Aesculape
Published: 1932
Copyrighted work available under Creative Commons Attribution only licence CC BY 4.0 http://creativecommons.org/licenses/by/4.0/

By Kristine Hansbery
Director of WSLH Proficiency Testing

With the recent Covid-19 outbreak our nation is realizing the importance of having a strong public health presence both to avert disaster and protect the wellbeing of our public. During these tumultuous times I am reminded of the words of Jon Snow from Game of Thrones, not to be confused with the “father” of epidemiology, John Snow. However, the John Snow of public health would probably agree with the Game of Thrones Jon Snow, that “There is only one war that matters. The Great War. And it is here.” Yes, the fight against the Coronavirus has become our great war and it is indeed here.

So, why is public health such an important part of this war against the pandemic? Using a historical lens, we can better understand the important role public health labs play in supporting clinical labs in this fight.

Tracing the conceptualization of “public health” and how it has translated into actions in the United Kingdom and the United States can illuminate the important role public health labs play in supporting clinical labs. In particular, the role of public health labs today in providing statistical analysis and reporting to prevent and respond to epidemics is salient to elucidate historically.

John Snow, the father of epidemiology, first made his mark on disease prevention with the “Broad Street pump.” In late August of 1853, cholera broke out in the Broad Street area of London. Snow believed the outbreak was linked to the communal pump located there. To prove his theory, he tracked and recorded incidences of cholera in and around the pump. This was the beginning of using statistics to define disease patterns so interventions could be performed.

The rise of epidemiology and subsequent interventions to stop the spread of disease, gave rise to the creation of government entities who could implement and enforce such mediations for the overall health of the public. The first public agency for health in the United States was the New York City Health Department, which was founded in 1866. This event in history marked the very beginning of the concept of “public health” in the United States. At the end of the 19th century, newly established state and local health departments in the United States began to establish laboratories to develop and apply the new scientific knowledge. (Winslow, 1923)

The early part of the 20th century in the United States saw the creation of federal programs of disease control, research and epidemiology, including the establishment of the Communicable Disease Center in 1946, now known as the Center for Disease Control and prevention (CDC). During this time, state and federal passed regulations to incorporate the concepts of sanitation and disease control using the scientific findings of public health labs.

Today, public health labs all over the U.S. work together under the CDC’s Laboratory Response Network (LRN) in order to quickly and efficiently respond to emerging infections and other public health emergencies. The Wisconsin State Lab of Hygiene (WSLH), which is the home of my organization WSLH Proficiency Testing, works closely with the CDC to provide reference and specialized testing services. Currently the Communicable Disease Division of WSLH is providing validations to help prepare clinical laboratories for Covid-19 testing.

What this dive into the history of public health has taught us is that the rise of epidemiology may have provided the foundation for public health, but social values, including community intervention and health goals, have brought about its system as we know it today. Collaborative partnerships and networks between public health labs and clinical labs will need to continue to grow to adapt and respond to today’s challenges in maintaining the health of our communities.

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